Celtics vs. Cavaliers odds, line: 2022 NBA picks, Oct. 28 predictions from proven computer model

Celtics vs. Cavaliers odds, line: 2022 NBA picks, Oct. 28 predictions from proven computer model

Updated: 5 months, 1 day, 2 hours, 13 minutes, 54 seconds ago

The Boston Celtics (3-1) will try to bounce back from their first loss of the season when they face the Cleveland Cavaliers (3-1) on Friday night. Boston was unable to complete its three-game road trip with a perfect record, losing to Chicago in a 120-102 final on Monday. Cleveland enters this contest on a three-game winning streak following a loss to Toronto in its opener. 

Tipoff is set for 7:30 p.m. ET at TD Garden. Boston is favored by 6.5 points in the latest Celtics vs. Cavaliers odds from Caesars Sportsbook, while the over/under is set at 218. Before entering any Cavaliers vs. Celtics picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four seasons. The model enters Week 2 of the 2022-23 NBA season on a stunning 91-63 roll on all top-rated NBA picks that dates back to last season, returning more than $2,100. Anyone following it has seen huge returns.

Now, the model has set its sights on Celtics vs. Cavaliers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Cavaliers vs. Celtics:

Celtics vs. Cavaliers spread: Celtics -6.5Celtics vs. Cavaliers over/under: 218 pointsCeltics vs. Cavaliers money line: Boston -260, Cleveland +210Celtics vs. Cavaliers picks: See picks here

Why the Celtics can cover

Boston is coming off a loss to Chicago, but the Celtics looked fantastic in their first three games, picking up wins against Philadelphia, Miami and Orlando. They made a run to the NBA Finals last season, so they have established themselves as one of the top teams in the league. Forward Jayson Tatum leads the way with 32.5 points, 8.3 rebounds and 3.5 assists per game. 

Tatum is joined by Jaylen Brown, who is averaging 24.0 points and 5.5 rebounds. Cleveland has only been on the road twice this season, with one of those games resulting in a 108-105 loss at Toronto. The Cavaliers are 3-12 in their last 15 road games and have gone winless in their last six trips to Boston. Boston will get to go up against a Cavs team missing one of its best players as Darius Garland is out with an eye injury.

Why the Cavaliers can cover

Boston is going to have a tough time matching up with Cleveland in the paint on Friday night, as forward Grant Williams will be serving a one-game suspension for making contact with an official on Monday. The Celtics are already without big man Robert Williams III due to offseason knee surgery, leaving them thin down low heading into this game. Cleveland has an outstanding duo of Jarrett Allen and Evan Mobley in the paint, giving the Cavaliers a big advantage. 

They also added star guard Donovan Mitchell from Utah in the offseason, and he scored at least 31 points in his first three outings with the team. Cleveland has been one of the top defensive teams in the league so far this year, and its offense is capable of doing damage down low in this matchup. The Celtics have only covered the spread twice in their last seven games, while Cleveland has covered five times in its last seven contests. 

How to make Cavaliers vs. Celtics picks

The model has simulated Celtics vs. Cavaliers 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread is hitting over 50% of the time. You can only see the pick at SportsLine.

So who wins Cavaliers vs. Celtics? And which side of the spread hits in over 50% of simulations? Visit SportsLine now to see which side of the Celtics vs. Cavaliers spread you need to jump on Friday, all from the model that has crushed its NBA picks, and find out.